Cell cycle arrest of a Caulobacter crescentus secA mutant
نویسندگان
چکیده
منابع مشابه
ppGpp and polyphosphate modulate cell cycle progression in Caulobacter crescentus.
Caulobacter crescentus differentiates from a motile, foraging swarmer cell into a sessile, replication-competent stalked cell during its cell cycle. This developmental transition is inhibited by nutrient deprivation to favor the motile swarmer state. We identify two cell cycle regulatory signals, ppGpp and polyphosphate (polyP), that inhibit the swarmer-to-stalked transition in both complex and...
متن کاملCaulobacter crescentus
shaped by their activity — both intrinsic and environment induced — and how these networks support the brain computations that underlie externally observable behavior. The second major challenge facing our young field will be applying the basic discoveries we are making to important real-world issues. It is a widely held view that understanding the brain bases of cognitive and behavioral develo...
متن کاملRegulated proteolysis of a transcription factor complex is critical to cell cycle progression in Caulobacter crescentus.
Cell cycle transitions are often triggered by the proteolysis of key regulatory proteins. In Caulobacter crescentus, the G1-S transition involves the degradation of an essential DNA-binding response regulator, CtrA, by the ClpXP protease. Here, we show that another critical cell cycle regulator, SciP, is also degraded during the G1-S transition, but by the Lon protease. SciP is a small protein ...
متن کاملDynamical Modeling of the Cell Cycle and Cell Fate Emergence in Caulobacter crescentus
The division of Caulobacter crescentus, a model organism for studying cell cycle and differentiation in bacteria, generates two cell types: swarmer and stalked. To complete its cycle, C. crescentus must first differentiate from the swarmer to the stalked phenotype. An important regulator involved in this process is CtrA, which operates in a gene regulatory network and coordinates many of the in...
متن کاملAnalysis of caulobacter crescentus lipids.
The lipids of Caulobacter crescentus, a procaryotic species which differentiates into stalked and swarmer cell types, were analyzed. Major lipid classes were purified by chromatography and identified by both chromatographic and chemical methods. Approximately half of the total lipid fraction of this organism consisted of glycolipis, which were primarily monoglucosyldiglyceride and an acylated g...
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ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 1994
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.176.16.4958-4965.1994